5. Research Compliance
Principle
Iowa State University is committed to ensuring that research conducted on or off
campus, including collaborative research with third parties, is in compliance
with University, local, state, federal and sponsor regulations. All research
protocols involving biohazards, animals or human subjects conducted at ISU and
ISU laboratories utilizing radioactive devices and/or materials require
institutional review and approval.
Guidelines
ISU's Research Compliance Officer oversees campus-wide research compliance
including four committees responsible for reviewing compliance. Additional
information can be found at www.compliance.iastate.edu
.
Committee On Animal Care (COAC)
All research involving the use of live vertebrate animals must be reviewed and
approved by the COAC prior to initiation of research. To receive Public Health
Service (PHS) funding and comply with the federal Animal Welfare Act, ISU must
have an established animal care and use program. The program must include 1) a
properly constituted and functioning Institutional Animal Care and Use
Committee; 2) self monitoring procedures; 3) a veterinary care program; 4) a
program for personnel training; 5) a program for management, environment and
housing for animals; and 6) appropriately maintained housing and support
facilities. Please see www.compliance.iastate.edu
for additional information.
Institutional Review Board (IRB)
All research involving the use of human subjects must be reviewed and approved
by the IRB prior to initiation of research. As part of ISU’s federal wide
assurance (FWA) with the Office of Human Research Protection, the IRB reviews
studies involving human research participants. As agreed in ISU’s FWA, all
projects must be reviewed regardless of funding source. Research involving
human subjects encompasses biomedical and clinical studies; social and
behavioral research, such as surveys; exercise and nutrition studies; learning
experiments; etc. Please see www.compliance.iastate.edu
for additional information.
Biohazards and Public Health Committee (BPHC)
All research protocols involving biohazards must be reviewed and approved by the
BPHC prior to initiation of research. As required by the May 7, 1986, Federal
Register and amendments, the BPHC serves as the institutional biosafety
committee in all matters involving recombinant DNA, human or animal pathogens,
or biological toxins. The BPHC also reviews the biological and public health
and safety programs at ISU and for assisting in the development of policies
that comply with federal, state, and local regulations and recommendations.
Please see www.compliance.iastate.edu
for additional information.
Radiation Safety
All laboratories using radioactive materials or radiation-producing devices must
be reviewed and approved by the Radiation Safety Committee (RSC) prior to
initiation of research. The principal function of the RSC is to assist in
establishing ISU policy for the safe use of radioactive materials and
radiation-producing devices that comply with federal, state, and local
regulations. Please see www.compliance.iastate.edu
for additional information.
Compliance HelpLine
For questions or concerns about research compliance, the Office of Research
Compliance has a confidential help line (515-294-9264), which is answered only
by the Research Compliance Officer.